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, 2013). As the above illustrations clearly show, Though selective the tetrad bioassay protocol isn't unique for CB1R activation inside the central anxious procedure, the presumed neural foundation underlying the “subjective substantial”, fueling the ingestion of cannabis preparations and various artificial cannabimimetics. Instead, the pharmacological specificity problem in the above mentioned described studies was approached by using drug discrimination, an assay we believe is highly appropriate for being familiar with the psychopharmacology of THC/marijuana as well as the modern addition of so called “designer cannabimimetics” in people.
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